(AGI) Tokyo, July 16 - The Tokyo Stock Exchange closed lower onWednesday following Wall Street's poor performance. Trading inNew York was weighed down by the Federal Reserve's warning overthe inflated prices of a number of social media and biotechstocks. The Nikkei index was down 0.1 percent at 15,739.30points, while the Topix fell 0.01 percent to 1,273.59 points. . .